Some fish such as tuna,especially bluefin,can carry high levels of mercury and can be hazardous when consumed in large quantities.Parasite infection by raw fish is rare in the modern world(less than 40 cases per year in the U.S.),and involves mainly three kinds of parasites:Clonorchis sinensis(a trematode/fluke),Anisakis(a nematode/round worm) and Diphyllobothrium(a cestode/tape worm).
In addition,some forms of sushi,notably puffer fugu,can cause severe poisoning if not prepared properly.
Also,some sushi ingredients and condiments such as soy sauce,contain high levels of sodium,posing a risk to those with hypertension or renal disorders.
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